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Catherine Limperopoulos PH.D.

Catherine Limperopoulos, Ph.D., is Center Director of Prenatal, Neonatal & Maternal Health Research and Director & Chief of the Developing Brain Institute (DBI) at Children’s National. Dr. Limperopoulos is also (tenured) Professor of Radiology, Neurology and Pediatrics and Professor of Obstetrics and Gynecology at the George Washington University (GWU) School of Medicine & Health Sciences.

Dr. Limperopoulos studies the causes and consequences of adverse prenatal environments and brain and placental development in high-risk fetal, preterm and infant populations. As Center Director, she will continue to develop novel tools and precision medicine solutions to diseases that have their origins in the womb but don’t fully manifest until adulthood. Central to her research is applying advanced MRI techniques to identify important biomarkers and to better elucidate the timing and evolution of impaired brain maturation, as well as the brain’s adaptive responses. Her lab leads the world in applying advanced imaging techniques to identify early brain and placental biomarkers of risk and resilience for neurodevelopmental impairment. Her goal is to develop early and reliable signals that can identify the high-risk fetus prior to irreversible brain injury. Dr. Limperopoulos also co-leads the Clark Parent & Child Network a project that links parents to needed resources and time-sensitive mental health support. The Network was underwritten by a transformational, $36 million investment. And powered by that funding, the DC Mother-Baby Wellness program she oversees has received more than 1,000 referrals in fewer than two years. She also was named the A. James & Alice B. Clark Foundation Distinguished Professor of Maternal-Infant Health, an appointment that honors her unique achievements and that supports her groundbreaking research to improve the lives of children and families.

DBI has assembled leading scientists and healthcare providers from across myriad disciplines and healthcare models (tertiary care to primary care) that are at the forefront of clinical research and translational efforts focused on accelerating screening, diagnosing, treating and preventing prenatal onset brain disorders to improve child health and well-being for life. She is an occupational therapist and pediatric neuroscientist who has demonstrated repeated successes in completing novel, patient-centered clinical and translational research in healthy and high-risk pregnant women and neurodiagnostic and neurodevelopmental surveillance in high-risk fetuses and preterm infants. In addition to funding from private donors, like the Clark Foundation, she has or has had funding from the National Institutes of Health (NIH), Canadian Institutes of Health Research, the Department of Defense, Patient-Centered Outcomes Research Institute and the Centers for Disease Control and Prevention. She has authored more than 170 peer-reviewed publications. She also leads the Integrating Special Populations Module of the Children’s National/GWU NIH Clinical and Translational Science Award, which focuses on improving recruitment and retention of disadvantaged women into preventive maternal-fetal clinical trials aimed at optimizing long-term, maternal-infant health and well-being.

Dr. Limperopoulos is founder and director of the DC Perinatal Consortium, which brings together multiple stakeholders from our regional (Washington, D.C.) healthcare partners in obstetrics, psychiatry and pediatrics and an established community advisory board with representation from low-income Black communities, including the DC Primary Care Association, Mary’s Center, Community of Hope, Unity Health Care, Mamatoto Village and Black patients, representatives with expertise in advocacy and policy. The overarching mission of this DC collaborative is to determine optimal delivery of screening and low-cost interventions aimed at reducing the striking health disparities experienced by low-income women in the District of Columbia.



Profile

Address: 111 Michigan Ave NW, Washington, DC 20010
Department: MRI Lab

Recent Publications & Presentations



2023 | May
De Asis-Cruz J, Limperopoulos C.
Harnessing the power of advanced fetal neuroimaging to understand in utero footprints for later neuropsychiatric disorders. Biol Psychiatry. 2023 May 15;93(10):867-879. doi: 10.1016/j.biopsych.2022.11.019. Epub 2022 Dec 5. PMID: 36804195.
https://pubmed.ncbi.nlm.nih.gov/36804195/
Whitehead MT*, Limperopoulos C, Schlatterer SD, Mulkey SB*, Fraser JL, du Plessis AJ.
Hippocampal rotation is associated with ventricular atrial size. Pediatr Radiol. 2023 May 15. doi: 10.1007/s00247-023-05687-6. Epub ahead of print. Erratum in: Pediatr Radiol. 2023 May 27;: PMID: 37183230. https://pubmed.ncbi.nlm.nih.gov/37183230/
Saeed H, Lu YC, Andescavage N, Kapse K, Andersen NR, Lopez C, Quistorff J, Barnett S, Henderson D, Bulas D, Limperopoulos C.
Influence of maternal psychological distress during COVID-19 pandemic on placental morphometry and texture. Sci Rep. 2023 May 10;13(1):7374. doi: 10.1038/s41598-023-33343-4. PMID: 37164993; PMCID: PMC10172401. https://pubmed.ncbi.nlm.nih.gov/37164993/
Kim JH, De Asis-Cruz J, Krishnamurthy D, Limperopoulos C.
Towards a more informative representation of the fetal-neonatal brain connectome using variational autoencoder
Elife. 2023 May 15;12:e80878. doi: 10.7554/eLife.80878. Epub ahead of print. PMID: 37184067 https://pubmed.ncbi.nlm.nih.gov/37184067/
2023 | April
Kim JH, De Asis-Cruz J, Kapse K, Limperopoulos C.
Systematic evaluation of head motion on resting-state functional connectivity MRI in the neonate. Hum Brain Mapp. 2023 Apr 1;44(5):1934-1948. doi: 10.1002/hbm.26183. Epub 2022 Dec 28. PMID: 36576333; PMCID: PMC9980896.
https://pubmed.ncbi.nlm.nih.gov/36576333/
Weiner S, Wu Y, Kapse K, Krishnamurthy D, Limperopoulos C.
Elevated maternal anxiety during the COVID-19 pandemic alters newborn hippocampal and amygdala development. Children’s National Hospital 13th Annual Research, Education and Innovation Week. Washington, D.C. April 2023. (Award-winning poster: Clinical research: Graduate student)
Lundberg RS, Basu SK, Andescavage N, Pradhan S, Ottolini KM, Kapse KJ, Limperopoulos C.
Early parenteral lipid intake improves cerebellar neurometabolism in preterm infants. Children’s National Hospital 13th Annual Research, Education and Innovation Week. Washington, D.C. April 2023. (Award-winning poster: Clinical research: Fellows/residents)
2023 | March
Chirumamilla VC, Hitchings L, Mulkey SB, Anwar T, Baker R, Larry Maxwell G, De Asis-Cruz J, Kapse K, Limperopoulos C, du Plessis A, Govindan RB.
Functional brain network properties of healthy full-term newborns quantified by scalp and source-reconstructed EEG. Clin Neurophysiol. 2023 Mar;147:72-80. doi: 10.1016/j.clinph.2023.01.005. Epub 2023 Jan 23. PMID: 36731349; PMCID: PMC9975070.
https://pubmed.ncbi.nlm.nih.gov/36731349/
2023 | February
Basu SK, Pradhan S, Sharker YM, Kapse KJ, Murnick J, Chang T, Lopez CA, Andescavage N, du Plessis AJ, Limperopoulos C.
Severity of prematurity and age impact early postnatal development of GABA and glutamate systems. Cereb Cortex. 2023 Feb 24:bhad046. doi: 10.1093/cercor/bhad046. Epub ahead of print. PMID: 36843135. https://pubmed.ncbi.nlm.nih.gov/36843135/
2023 | January
Bann CM, Newman JE, Okoniewski KC, Clarke L, Wilson-Costello D, Merhar S, Mack N, DeMauro S, Lorch S, Ambalavanan N, Limperopoulos C, Poindexter B, Walsh M, Davis JM.
Psychometric properties of the Prenatal Opioid Use Perceived Stigma Scale and its use in prenatal care. J Obstet Gynecol Neonatal Nurs. 2023 Mar;52(2):150-158. doi: 10.1016/j.jogn.2022.12.002. Epub 2023 Jan 22. PMID: 36696952. https://pubmed.ncbi.nlm.nih.gov/36696952/
2022
Wu Y, Espinosa KM, Barnett SD, Kapse A, Quistorff JL, Lopez C, Andescavage N, Pradhan S, Lu YC, Kapse K, Henderson D, Vezina G, Wessel D, du Plessis AJ, Limperopoulos C.
Association of elevated maternal psychological distress, altered fetal brain, and offspring cognitive and social-emotional outcomes at 18 months. JAMA Netw Open. 2022 Apr 1;5(4):e229244. doi: 10.1001/jamanetworkopen.2022.9244. PMID: 35486403; PMCID: PMC9055453. https://pubmed.ncbi.nlm.nih.gov/35486403/
2022
Largent A, De Asis-Cruz J, Kapse K, Barnett SD, Murnick J, Basu S, Andersen N, Norman S, Andescavage N, Limperopoulos C.
Automatic brain segmentation in preterm infants with post-hemorrhagic hydrocephalus using 3D Bayesian U-Net Hum Brain Mapp. 2022 Jan 13. doi: 10.1002/hbm.25762. Epub ahead of print. PMID: 35023255 https://pubmed.ncbi.nlm.nih.gov/35023255/
2022
Limperopoulos C, Wessel DL, du Plessis AJ
Understanding the maternal-fetal environment and the birth of prenatal pediatrics J Am Heart Assoc. 2022 Jan 11:e023807. doi: 10.1161/JAHA.121.023807. Epub ahead of print. PMID: 35014863 https://pubmed.ncbi.nlm.nih.gov/35014863/
2022
Basu SK, Pradhan S, Barnett SD, Mikkelsen M, Kapse KJ, Murnick J, Quistorff JL, Lopez CA, du Plessis AJ, Limperopoulos C
Regional differences in gamma-aminobutyric acid and glutamate concentrations in the healthy newborn brain AJNR Am J Neuroradiol. 2022 Jan;43(1):125-131. doi: 10.3174/ajnr.A7336. Epub 2021 Nov 11. PMID: 34764083 https://pubmed.ncbi.nlm.nih.gov/34764083/
2021
Schlatterer SD, Govindan RB, Murnick J, Barnett SD, Lopez C, Donofrio MT, Mulkey SB, Limperopoulos C, du Plessis AJ
In infants with congenital heart disease autonomic dysfunction is associated with pre-operative brain injury Pediatr Res. 2021 Dec 28. doi: 10.1038/s41390-021-01931-7. Epub ahead of print. PMID: 34963700 https://pubmed.ncbi.nlm.nih.gov/34963700/
2021
Wu Y, Lu YC, Kapse K, Jacobs M, Andescavage N, Donofrio MT, Lopez C, Quistorff JL, Vezina G, Krishnan A, du Plessis AJ, Limperopoulos C
In utero MRI identifies impaired second trimester subplate growth in fetuses with congenital heart disease
Cereb Cortex. 2021 Oct 28:bhab386. doi: 10.1093/cercor/bhab386. Epub ahead of print. PMID: 34882775 https://pubmed.ncbi.nlm.nih.gov/34882775/
2021
Espinosa KM, Julian M, Wu Y, Lopez C, Donofrio MT, Krishnan A, Goudar S, Bowers S, Douglas-Barnett S, Limperopoulos C, Le HN
"The Mental Health Piece is Huge": perspectives on developing a prenatal maternal psychological intervention for congenital heart disease
Cardiol Young. 2021 Sep 30:1-8. doi: 10.1017/S1047951121004030. Epub ahead of print. PMID: 34588092. https://pubmed.ncbi.nlm.nih.gov/34588092/
2021
Andescavage N, Limperopoulos C.
Emerging placental biomarkers of health and disease through advanced magnetic resonance imaging (MRI)
Exp Neurol. 2021 Sep 22:113868. doi: 10.1016/j.expneurol.2021.113868. Epub ahead of print. PMID: 34562472. https://pubmed.ncbi.nlm.nih.gov/34562472/
2021
Brossard-Racine M, Limperopoulos C.
Cerebellar injury in premature neonates: Imaging findings and relationship with outcome. Semin Perinatol. 2021 Aug 21:151470. doi: 10.1016/j.semperi.2021.151470. Epub ahead of print. PMID: 34462245. https://pubmed.ncbi.nlm.nih.gov/34462025/
2021
Wu Y, Andescavage N, Lopez C, Quistorff JL, Donofrio MT, du Plessis AJ, Limperopoulos C.
Maternal mental distress and cortisol levels in pregnancies with congenital heart disease. Cardiol Young. 2021 Aug 31:1-5. doi: 10.1017/S1047951121003504. Epub ahead of print. PMID: 34462025. https://pubmed.ncbi.nlm.nih.gov/34462025/
2021
Kosiorek A, Donofrio MT, Zurakowski D, Reitz JG, Tague L, Murnick J, Axt-Fliedner R, Limperopoulos C, Yerebakan C, Carpenter JL Predictors of Neurological Outcome Following Infant Cardiac Surgery Without Deep Hypothermic Circulatory Arrest Pediatr Cardiol. 2021 Aug 17. doi: 10.1007/s00246-021-02693-z. Epub ahead of print. PMID: 34402933 https://pubmed.ncbi.nlm.nih.gov/34402933/
2021
Andescavage N, Kapse K, Lu YC, Barnett SD, Jacobs M, Gimovsky AC, Ahmadzia H, Quistorff J, Lopez C, Andersen NR, Bulas D, Limperopoulos C
Normative placental structure in pregnancy using quantitative Magnetic Resonance Imaging
Placenta. 2021 Jul 31;112:172-179. doi: 10.1016/j.placenta.2021.07.296. Epub ahead of print. PMID: 34365206. https://pubmed.ncbi.nlm.nih.gov/34365206/
2021 | July
Hui SCN, Mikkelsen M, Zöllner HJ, Ahluwalia V, Alcauter S, Baltusis L, Barany DA, Barlow LR, Becker R, Berman JI, Berrington A, Bhattacharyya PK, Blicher JU, Bogner W, Brown MS, Calhoun VD, Castillo R, Cecil KM, Choi YB, Chu WCW, Clarke WT, Craven AR, Cuypers K, Dacko M, de la Fuente-Sandoval C, Desmond P, Domagalik A, Dumont J, Duncan NW, Dydak U, Dyke K, Edmondson DA, Ende G, Ersland L, Evans CJ, Fermin ASR, Ferretti A, Fillmer A, Gong T, Greenhouse I, Grist JT, Gu M, Harris AD, Hat K, Heba S, Heckova E, Hegarty JP 2nd, Heise KF, Jacobson A, Jansen JFA, Jenkins CW, Johnston SJ, Juchem C, Kangarlu A, Kerr AB, Landheer K, Lange T, Lee P, Levendovszky SR, Limperopoulos C, Liu F, Lloyd W, Lythgoe DJ, Machizawa MG, MacMillan EL, Maddock RJ, Manzhurtsev AV, Martinez-Gudino ML, Miller JJ, Mirzakhanian H, Moreno-Ortega M, Mullins PG, Near J, Noeske R, Nordhøy W, Oeltzschner G, Osorio-Duran R, Otaduy MCG, Pasaye EH, Peeters R, Peltier SJ, Pilatus U, Polomac N, Porges EC, Pradhan S, Prisciandaro JJ, Puts NA, Rae CD, Reyes-Madrigal F, Roberts TPL, Robertson CE, Rosenberg JT, Rotaru DG, O'Gorman Tuura RL, Saleh MG, Sandberg K, Sangill R, Schembri K, Schrantee A, Semenova NA, Singel D, Sitnikov R, Smith J, Song Y, Stark C, Stoffers D, Swinnen SP, Tain R, Tanase C, Tapper S, Tegenthoff M, Thiel T, Thioux M, Truong P, van Dijk P, Vella N, Vidyasagar R, Vovk A, Wang G, Westlye LT, Wilbur TK, Willoughby WR, Wilson M, Wittsack HJ, Woods AJ, Wu YC, Xu J, Lopez MY, Yeung DKW, Zhao Q, Zhou X, Zupan G, Edden RAE, Nakajima SL, Honda S
Frequency drift in MR spectroscopy at 3T
Neuroimage. 2021 Jul 24;241:118430. doi: 10.1016/j.neuroimage.2021.118430. Epub ahead of print. PMID: 34314848. https://pubmed.ncbi.nlm.nih.gov/34314848/
2021
Hui SCN, Mikkelsen M, Zöllner HJ, Ahluwalia V, Alcauter S, Baltusis L, Barany DA, Barlow LR, Limperopoulos C, Edden RAE
Frequency drift in MR spectroscopy at 3T. Neuroimage
2021 Nov 1;241:118430. doi: 10.1016/j.neuroimage.2021.118430. Epub 2021 Jul 24. PMID: 34314848; PMCID: PMC8456751. https://pubmed.ncbi.nlm.nih.gov/34314848/
2021
De Asis-Cruz, J, Barnett, S.D., Kim, J.H. and Limperopoulos, C.
Functional Connectivity-Derived Optimal Gestational-Age Cut Points for Fetal Brain Network Maturity
11(7), p.921.2021. https://www.mdpi.com
2021
Ottolini KM, Andescavage N, Kapse K, Jacobs M, Murnick J, VanderVeer R, Basu S, Said M, Limperopoulos C
Early lipid intake improves cerebellar growth in very low-birth-weight preterm infants.
JPEN J Parenter Enteral Nutr. 2021 Mar;45(3):587-595. doi: 10.1002/jpen.1868. Epub 2020 Jun 4. PMID: 32384168. https://pubmed.ncbi.nlm.nih.gov/32384168/
2021
De Asis-Cruz J, Andersen N, Kapse K, Khrisnamurthy D, Quistorff J, Lopez C, Vezina G, Limperopoulos C
Global Network Organization of the Fetal Functional Connectome.
Cereb Cortex. 2021 May 10;31(6):3034-3046. doi: 10.1093/cercor/bhaa410. PMID: 33558873; PMCID: PMC8107792. https://pubmed.ncbi.nlm.nih.gov/33558873/
2021
De Asis-Cruz J and Limperopoulos C.
Chapter 24 - Linking congenital heart disease and brain functional connectivity in newborns.
In Martin CR, Preedy VR, Rajendram R, eds. Diagnosis, Management and Modeling of Neurodevelopmental Disorders: Academic Press; 2021: 275-284. ISBN 9780128179888 https://www.sciencedirect.com/
2021
Gold S, Kapse K, Lopez C, Quistorff J, Downs S, Iqbal S, Limperopoulos C, Andescavage N. In vivo placental function in pregnancies complicated by maternal diabetes mellitus. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 4, 2021.
2021
Andescavage N, Kushal K, Lu Y-C, Barnett S, Saeed H, Quistorff J, Lopez C, Limperopoulos C In-vivo changes of placental development during the COVID19 pandemic. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 4, 2021.
2021
De Asis-Cruz J, Lopez C, Kapse K, Quistorff J, Vezina G, Donofrio M, Limperopoulos C In-utero MRI identifies altered resting state networks in fetuses with complex congenital heart disease. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 4, 2021.
2021
Lu Y-C, Andescavage N, Saeed H, Quistorff J, Lopez C, Henderson D, Kapse K, Vezina G, du Plessis AJ, Limperopoulos C Structural changes of the human fetal brain during the COVID-19 pandemic. Society for Pediatric Research (SPR) Plenary Series: Best of SPR Featured Abstracts. Pediatric Academic Societies 2021 Virtual Meeting, May 4, 2021.
2021
Ahmadzia HK, Lu Y-C, Barak S, Quistorff J, Lopez C, Kapse K, Limperopoulos C, Andescavage N Optimizing abnormal placentation detection prenatally using quantitative MRI. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 4, 2021.
2021
Cook KM, De Asis-Cruz J, Lopez C, Quistorff J, Kapse K, Andresen N, Vezina G, Limperopoulos C In utero MRI differentiates male and female human fetal brain functional connectivity. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 3, 2021.
2021
Andescavage N, Bullen T, Liggett M, Barnett S, Espinosa K, Kapse A, Kapse K, Ahmadzia H, Quistorff J, Lopez C, Limperopoulos C Relating fetal brain development and neonatal neurobehavior in pregnancies complicated by fetal growth restriction. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 3, 2021.
2021
Lu Y-C, Andescavage N, Saeed H, Kapse K, Andersen N, Lopez C, Henderson D, Bulas D, du Plessis AJ, Limperopoulos C Influence of the COVID-19 pandemic on human placental morphology and texture. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 3, 2021.
2021
Pradhan S, Niforatos-Andescavage N, Saeed H, Barnett S, Kapse K, Andersen N, Quistorff J, Lopez C, Vezina G, Limperopoulos C Impaired fetal brain metabolism in pregnancies complicated by elevated maternal stress during the COVID-19 pandemic. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 2, 2021.
2021
Basu S, Kapse K, Espinosa K, Kapse A, Norman S, Fischer D, Barnett S, Andescavage N, Limperopoulos C Relationship of postnatal medications with regional brain volume and cognition-neurobehavior. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 2, 2021.
2021
Lu Y-C, Andescavage N, Kapse K, Andersen N, Lopez C, Quistorff J, Henderson D, Bulas D, Krishnan A, Donofrio MT, du Plessis AJ, Limperopoulos C Maternal anxiety alters in vivo placental morphology and texture in pregnancies complicated by fetal congenital heart disease. Platform presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 1, 2021.
2021
Basu S, Espinosa K, Pradhan S, Kapse K, De-Asis Cruz J, Kapse A, Norman S, Fischer D, Andescavage N, Limperopoulos C Cerebellar structure, function and neurodevelopmental outcomes in very preterm infants. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
2021
Schlatterer SD, Govindan RB, Murnick J, Barnett SD, Lopez C, Al-Shargabi T, Donofrio MT, Mulkey SB, Limperopoulos C, du Plessis AJ. Early heart rate variability correlates with pre-operative brain injury score in infants with congenital heart disease. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
2021
Pradhan S, Kapse K, Niforatos-Andescavage N, Quistorff J, Lopez C, Limperopoulos C. Increased brain lactate in fetuses of pregnant women with diabetes. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
2021
Andescavage N, Liggett M, Barnett S, Espinosa K, Kapse A, Kapse K, Ahmadzia H, Quistorff J, Lopez C, Limperopoulos C. Impaired prenatal cerebellar growth predicts neurodevelopmental outcomes in growth restricted fetuses. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
2021
Lopez, C, Quistorff J, Saeed H, Barnett S, Henderson D, Andescavage N, Limperopoulos C. Changes in psychological distress profiles in Hispanic and African American women before and during the COVID-19 pandemic. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
2021
Axel Largent PhD, Kushal Kapse MS, Scott D. Barnett PhD, Josepheen De Asis‐Cruz MD, PhD, Matthew Whitehead MD, Jonathan Murnick MD, PhD, Li Zhao PhD, Nicole Andersen BA, Jessica Quistorff MPH, Catherine Lopez MS, Catherine Limperopoulos PhD
Image Quality Assessment of Fetal Brain MRI Using Multi‐Instance Deep Learning Methods
[published online ahead of print, 2021 Apr 23]. J Magn Reson Imaging 2021 Apr 23. doi: 10.1002/jmri.27649. https://onlinelibrary.wiley.com
2021
Zun Z, Kapse K, Jacobs M, Basu S, Said M, Andersen N, Murnick J, Chang T, du Plessis A, Limperopoulos C.
Longitudinal Trajectories of Regional Cerebral Blood Flow in Very Preterm Infants during Third Trimester Ex Utero Development Assessed with MRI. Radiology. 2021 Mar 30:202423. doi: 10.1148/radiol.2021202423. Epub ahead of print. PMID: 33787337. https://pubmed.ncbi.nlm.nih.gov/33787337/
2021
Lu YC, Kapse K, Andersen N, Quistorff J, Lopez C, Fry A, Cheng J, Andescavage N, Wu Y, Espinosa K, Vezina G, du Plessis A, Limperopoulos C.
Association between socioeconomic status and in utero fetal brain development. JAMA Network Open. Published 2021, Mar 1;4(3):e213526. doi: 10.1001/jamanetworkopen.2021.3526. PMID: 33779746. https://pubmed.ncbi.nlm.nih.gov/33779746/
2020
De Asis-Cruz J, Krishnamurthy D, Zhao L, Kapse K, Vezina G, Andescavage N, Quistorff J, Lopez C, Limperopoulos C.
Association of prenatal maternal anxiety with fetal regional brain connectivity JAMA Network Open. Published 2020, Dec. 7;3(12):e2022349. doi:10.1001/jamanetworkopen.2020.22349 https://pubmed.ncbi.nlm.nih.gov/33284334/
2020
De Asis-Cruz J, Kapse K, Basu SK, Said M, Scheinost D, Murnick J, Chang T, du Plessis A, Limperopoulos C.
Functional brain connectivity in ex utero premature infants compared to in utero fetuses
[published online ahead of print, 2020 Jun 11]. Neuroimage. 2020;219:117043. doi:10.1016/j.neuroimage.2020.117043 https://pubmed.ncbi.nlm.nih.gov/32534962/
2020
Ottolini KM, Andescavage N, Kapse K, Jacobs M, Murnick J, VanderVeer R, Basu S, Said M, Limperopoulos C.
Early lipid intake improves cerebellar growth in very low-birth-weight preterm infants
[published online ahead of print, 2020 May 8]. JPEN J Parenter Enteral Nutr. 2020;10.1002/jpen.1868. doi:10.1002/jpen.1868 https://pubmed.ncbi.nlm.nih.gov/32384168/
2020
Andescavage N, You W, Jacobs M, Kapse K, Quistorff J, Bulas D, Ahmadzia H, Gimovsky A, Baschat A, Limperopoulos C.
Exploring in vivo placental microstructure in healthy and growth-restricted pregnancies through diffusion-weighted magnetic resonance imaging. Placenta.2020 Apr;93:113-118. doi: 10.1016/j.placenta.2020.03.004. Epub 2020 Mar 6. https://pubmed.ncbi.nlm.nih.gov/32250735/
2020
Wu Y, Stoodley C, Brossard-Racine M, Kapse K, Vezina G, Murnick J, du Plessis, AJ, Limperopoulos C.
Altered local cerebellar and brainstem development in preterm infants. Neuroimage. 2020 Jun;213:116702. doi: 10.1016/j.neuroimage.2020.116702. Epub 2020 Mar 5. https://pubmed.ncbi.nlm.nih.gov/32147366/
2020
Fumagalli M, Parodi A, Ramenghi L, Limperopoulos C, Steggerda S.
Ultrasound of acquired posterior fossa abnormalities in the newborn. Pediatric Research. 2020 Mar;87 (Supple 1):25-36. doi: 10.1038/s41390-020-0778-9. PMID: 32218537. https://pubmed.ncbi.nlm.nih.gov/32218537/
2020
Wu Y, Lu YC, Jacobs M, Pradhan S, Kapse K, Zhao L, Andescavage N, Vezina G, du Plessis A, Limperopoulos C.
Association of prenatal maternal psychological distress with fetal brain growth, metabolism, and cortical maturation. JAMA Network Open. 2020 Jan 3;3(1):e1919940. doi: 10.1001/jamanetworkopen.2019.19940. PMC6991285 https://pubmed.ncbi.nlm.nih.gov/31995213/
2019
Wu Y, Kapse K, Jacobs M, Andescavage N, Donofrio MT, Krishnan A, Vezina G, Wessel D, du Plessis A, Limperopoulos C.
Association of maternal psychological distress with in utero brain development in fetuses with congenital heart disease. JAMA Pediatrics. 2020 Jan 13; doi:10.1001/jamapediatrics.2019.5316 PMCID: PMC6990726 https://pubmed.ncbi.nlm.nih.gov/31930365/
2020
Ottolini KM, Andescavage N, Kapse K, Jacobs M, Limperopoulos C.
Improved brain growth and microstructural development in breast milk-fed very low birth weight premature infants. Acta Paediatrica. 2020 Jan 10. doi: 10.1111/apa.15168. [Epub ahead of print] https://pubmed.ncbi.nlm.nih.gov/31922288/
2020
You W, Andescavage N, Kapse K, Donofrio MT, Jacobs M, Limperopoulos C.
Hemodynamic responses of the placenta and brain to maternal hyperoxia in fetuses with congenital heart disease by using Blood Oxygen–Level Dependent MRI. Radiology 2020 Jan; 294(1):141-148. doi: 10.1148/radiol.2019190751. Epub 2019 Nov 5. https://pubmed.ncbi.nlm.nih.gov/31687920/
2019
Bouyssi-Kobar M, De Asis-Cruz J, Murnick J, Chang T, Limperopoulos C.
Altered functional brain network integration, segregation and modularity in very preterm infants at term equivalent age. Journal of Pediatrics 2019;213:13-21.e1. doi:10.1016/j.jpeds.2019.06.030 https://pubmed.ncbi.nlm.nih.gov/31358292/
2019
Ottolini KM, Andescavage N, Keller S, Limperopoulos C.
Nutrition and the developing brain: the road to optimizing early neurodevelopment: a systematic review. Pediatric Research. 2019 Jul 26. doi: 10.1038/s41390-019-0508-3. [Epub ahead of print] PMID: 31349359 https://pubmed.ncbi.nlm.nih.gov/31349359/
2019
Andescavage N, Dahdouh S, Jacobs M, Yewale S, Bulas D, Iqbal S, Baschat A, Limperopoulos C.
In vivo textural and morphometric analysis of placental development in healthy & growth-restricted pregnancies using magnetic resonance imaging. Pediatrics Research. 2019 Jun 25; 85(7):974-81. doi: 10.1038/s41390-019-0311-1. Epub 2019 Jan 25. PMCID: PMC6531319 https://pubmed.ncbi.nlm.nih.gov/30700836/
2019
Schlatterer SD, Murnick J, Jacobs M, White L, Donofrio MT, Limperopoulos C.
Placental pathology and neuroimaging correlates in neonates with congenital heart disease. Scientific Reports. 2019 Mar 11;9(1):4137. doi: 10.1038/s41598-019-40894-y. PMCID: PMC6411739 https://pubmed.ncbi.nlm.nih.gov/30858514/
2019
Basu S, Pradhan S, Kapse K, McCarter R, Murnick J, Chang T, Limperopoulos C.
Third trimester cerebellar metabolite concentrations are decreased in very premature infants with structural injury. Scientific Reports. 2019 Feb 4;9(1):1212. doi: 10.1038/s41598-018-37203-4. https://pubmed.ncbi.nlm.nih.gov/30718546/
2019
You W, Andescavage N, Kapse K, Donofrio M, Jacobs M, Limperopoulos C.
Altered hemodynamic responses of the placenta and fetal brain to maternal hyperoxia in the fetus with congenital heart disease. Circulation. 2019 Jan 10. (Accepted)
2019
Brossard-Racine M, McCarter R, Murnick J, Tinkelman L, Vezina G, Limperopoulos C.
Early extra-uterine exposure alters regional cerebellar growth in infants born preterm. NeuroImage: Clinical. 2019;21:101646. doi: 10.1016/j.nicl.2018.101646. Epub 2018 Dec 19 https://pubmed.ncbi.nlm.nih.gov/30630759/
2019
Krishnan A, Tague L, Rudra H, Pradhan S, Vezina G, Limperopoulos C.
Clinical course of a fetus with hypoplastic left heart syndrome and premature ductal constriction. Cardiol Young. 2018 Dec 27:1-3. doi: 10.1017/S1047951118001701. [Epub ahead of print] https://pubmed.ncbi.nlm.nih.gov/30587271/
2018
Hernandez-Castillo C, Limperopoulos C, Diedrichsen J.
A representative template of the neonatal cerebellum. NeuroImage. 2018 Sep 19;184:450-454. doi: 10.1016/j.neuroimage.2018.09.048. PMID 30243975 https://pubmed.ncbi.nlm.nih.gov/30243975/
2018
You W, Xu F, Limperopoulos C.
Linear convolution model of fetal circulation for hemodynamic responses to maternal hyperoxia using in utero functional MRI. Biomedical Imaging (ISBI 2018), 2018 IEEE 15th International Symposium on Biomedical Imaging. 2018 Apr;2018:1284-7. doi: 10.1109/ISBI.2018.8363806 https://pubmed.ncbi.nlm.nih.gov/29899816/
2018
Bouyssi-Kobar M, Brossard-Racine M, Jacobs M, Murnick J, Chang T, Limperopoulos C.
Regional microstructural organization of the cerebral cortex is affected by preterm birth. NeuroImage:Clinical. 2018;18:871-880. doi: 10.1016/j.nicl.2018.03.020 https://pubmed.ncbi.nlm.nih.gov/29876271/
2018
Mahdi E, Murnick J, Limperopoulos C.
Cerebral perfusion is perturbed by preterm birth and brain injury. American Journal of Neuroradiology. 2018; 39(7):1330-1335. PMID: 2974820 https://pubmed.ncbi.nlm.nih.gov/29748205/
2018
Zun Z, Limperopoulos C.
Placental perfusion imaging using velocity selective arterial spin labeling. Magnetic Resonance in Medicine. 2018 Sep;80(3):1036-1047. PMID:29436733 https://pubmed.ncbi.nlm.nih.gov/29436733/


Book Chapters

2021
De Asis-Cruz J and Limperopoulos C. Chapter 24 - Linking congenital heart disease and brain functional connectivity in newborns. In Martin CR, Preedy VR, Rajendram R, eds
Diagnosis, Management and Modeling of Neurodevelopmental Disorders Academic Press; 2021: 275-284. ISBN 9780128179888 https://doi.org/10.1016/B978-0-12-817988-8.00024-5